Musculoskeletal syndromes

Displaying results 1-10 of 180

• Therapeutics:

  In people with hand osteoarthritis, chondroitin sulphate therapy for 6 months improves pain and function compared with placebo

  • Jean-Yves Reginster

  Evid. Based Med.  2012;  doi:10.1136/ebmed-2011-100515
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• Therapeutics:

  Systematic review of observational studies finds increased risk of fracture among older adults taking a proton pump inhibitor

  • Peter Vestergaard

  Evid. Based Med.  2012;17:39-40  doi:10.1136/ebm.2011.100114
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• Payer decision-making with limited comparative and cost effectiveness data: the case of new pharmacological treatments for gout

  • Michele Meltzer,
  • Laura T Pizzi,
  • Eric Jutkowitz

  Evid. Based Med.  2012;  doi:10.1136/ebmed-2011-100065
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• Surrogate outcomes are associated with low methodological quality of studies of rheumatoid arthritis treated with antitumour necrosis factor agents: a systematic review

  • Moacyr Roberto Cuce Nobre,
  • Frnanda Marques da Costa

  Evid. Based Med.  2012;17:3-7  doi:10.1136/ebm-2011-100058
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• Therapeutics:

  Calcium supplements may increase the risk of cardiovascular events in postmenopausal women

  • Barbara J Boucher

  Evid. Based Med.  2012;17:16-17  doi:10.1136/ebm.2011.100113
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• Therapeutics:

  Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors

  • George Triadafilopoulos

  Evid. Based Med.  2012;17:17-18  doi:10.1136/ebmed-2011-100115
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• Prognosis:

  Patients treated with aspirin after a first myocardial infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events

  • David N Juurlink

  Evid. Based Med.  2012;17:33-34  doi:10.1136/ebmed.2011.100263
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• Therapeutics:

  Some oral antidiabetic medications may prevent type 2 diabetes in people at high risk for it, but the evidence is insufficient to determine whether the potential benefits outweigh the possible risks

  • Andrew J Krentz

  Evid. Based Med.  2011;  doi:10.1136/ebmed-2011-100332
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• Aetiology:

  Older women who use bisphosphonate for longer than 5 years may have increased odds of a subtrochanteric or femoral shaft fracture, but absolute risk is low

  • Bo Abrahamsen

  Evid. Based Med.  2011;16:168-169  doi:10.1136/ebm.2011.000013
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• Therapeutics:

  Acute otitis media: antibiotics are moderately effective and mildly increase the risk of adverse effects; prevalence of different causative bacteria changed after introduction of the heptavalent pneumococcal conjugate vaccine

  • Colin Sox

  Evid. Based Med.  2011;16:181-182  doi:10.1136/ebm1407
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