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Review: sparse high quality evidence supports surgery for obesity

Key Words: obesity

The first 150 words of the full text of this article appear below.

METHODS
Data sources: Medline and EMBASE/Excerpta Medica (to July 2003), and existing systematic reviews.

Study selection and assessment: randomised controlled trials (RCTs), controlled clinical trials, cohort studies, and case series that evaluated surgical treatment of obesity.

Outcomes: weight loss, mortality, complication rates, and control of major obesity related comorbid conditions.

MAIN RESULTS
147 studies met the inclusion criteria: 89 reported weight loss results (mean age 38 y, 75% women, baseline body mass index 47 kg/m²), 134 reported mortality rates, and 128 reported complications rates. The analysis focused on the most common currently performed surgical procedures: Roux-en-Y gastric bypass (RYGB) (including open and laparoscopic), vertical banded gastroplasty (VBG), adjustable gastric banding, and biliopancreatic diversion (including duodenal switch).

Weight loss. 3 RCTs compared surgery with no surgery. 2 older RCTs favoured surgery: 1 RCT from 1984 showed greater weight loss at 24 months with horizontal gastroplasty plus diet than with diet alone (31 v . . . [Full text of this article]

Kurt A Kennel, MD

Mayo Clinic, Rochester, Minnesota, USA.