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Evidence-Based Medicine 2005;10:149; doi:10.1136/ebm.10.5.149
Copyright © 2005 by the BMJ Publishing Group Ltd.

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Diagnosis

A decrease of >=2 points on the Mini-Mental State Examination was the best determinant of delirium in elderly patients admitted to hospital

O’Keeffe ST, Mulkerrin EC, Nayeem K, et al. Use of serial Mini-Mental State Examinations to diagnose and monitor delirium in elderly hospital patients. J Am Geriatr Soc 2005;53:867–70.[CrossRef][Medline]

Q In elderly patients admitted to hospital, are serial Mini-Mental State Examinations (MMSEs) accurate for diagnosing delirium?

Clinical impact ratings Internal medicine ******{star} Geriatrics *****{star}{star}

Key Words: delirium • geriatric assessment • hospitalisation

The first 150 words of the full text of this article appear below.

METHODS
{ebmflochart.f1}Design: blinded comparison of MMSE with geriatrician diagnosis of delirium.

{ebmglobe.f1}Setting: a hospital in Galway, Republic of Ireland.

{ebmpatient.f1}Patients: 165 patients who were >=65 years of age (mean age 79 y, 46% women) and were admitted to hospital from the accident and emergency department. 36 patients had dementia. The most common diagnoses were respiratory (n = 68), cardiovascular (n = 35), gastrointestinal (n = 20), and cerebrovascular (n = 19). Exclusion criteria: severe aphasia or deafness, poor prognosis, or hospital stay <6 days.

{ebmtestube.f1}Description of test: MMSE was given on day 1 and day 6. The MMSE used was adapted and validated for use in Irish patients.

{ebmgold.f1}Diagnostic standard: an experienced consultant geriatrician interviewed patients on days 1 and 6 and determined the presence or absence of delirium, dementia, or both. Delirium was diagnosed using the Confusion Assessment Method diagnostic algorithm. The geriatrician did not know the MMSE results.

{ebmruler.f1}Outcomes: . . . [Full text of this article]

Suzanne D Fields, MD

SUNY Stony Brook School of Medicine
Stony Brook, New York, USA







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