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Pharmacist led, primary care based disease management reduced risk factors and improved glycaemic control in diabetes
Rothman RL, Malone R, Bryant B, et al. A randomized trial of a primary care-based disease management program to improve cardiovascular risk factors and glycated hemoglobin levels in patients with diabetes. Am J Med 2005;118:276–84.[CrossRef][Medline]
Q In vulnerable patients with poorly controlled type 2 diabetes mellitus, does a pharmacist led, primary care-based, disease management programme reduce cardiovascular risk factors and improve glycaemic control?
Internal medicine Cardiology Endocrine
Key Words: blood pressure • diabetes mellitus (type 2) • haemoglobin A (glycosylated)
| The first 150 words of the full text of this article appear below. |
Design:
randomised controlled trial.
Allocation:
{concealed*}
.
Blinding:
blinded (outcome assessors {and data collectors}
).
Follow up period:
1 year.
Setting:
University of North Carolina General Internal Medicine Practice, Chapel Hill, North Carolina, USA.
Patients:
217 English speaking patients who were 
18 years of age, had a clinical diagnosis of type 2 diabetes, had poor glucose control (glycated haemoglobin [HbA1C] concentration 8.0%), and had a life expectancy >6 months.
Intervention:
primary care disease management programme (n = 112) or usual care (n = 110). The intervention consisted of usual care supplemented with intensive diabetes management; 3 clinical pharmacists who had training in outpatient disease management delivered intensive educational sessions and used evidence-based algorithms and proactive management of clinical parameters. See www.evidence-basedmedicine.com.
Outcomes:
blood pressure (BP), HbA1C concentrations, aspirin use, and lipid concentrations.
Patient follow up:
89% at 1 year (intention to treat analysis).
Systolic and diastolic BP,
Mayo Clinic Rochester
>Rochester, Minnesota, USA
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