HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Talley, N. J Search for Related Content PubMed Articles by Talley, N. J

Review: prompt endoscopy is not a cost effective strategy for initial management of dyspepsia

Clinical impact ratings GP/FP/Primary care IM/Ambulatory care Gastroenterology

Key Words: dyspepsia • endoscopy • gastrointestinal • helicobacter pylori

The first 150 words of the full text of this article appear below.

METHODS
Data sources: a randomised controlled trial (RCT) register established by the Dyspepsia Trials Collaborators’ Group supplemented by searches of the Cochrane database of RCTs and Medline (all up to December 2003).

Study selection and assessment: RCTs that compared a prompt endoscopy strategy with a test and treat approach for the initial management of dyspepsia in adults in primary care or on first referral to secondary care, and reported relevant outcomes.

Outcomes: total dyspepsia symptom score, presence of dyspepsia, cost (in 2003 US dollars), and incremental net benefit at 12 months.

MAIN RESULTS
5 RCTs (n = 1924) (mean age 41 years, 50% men) met the selection criteria. Effects of the intervention on dyspepsia symptoms were pooled using meta-analysis of individual patient data. The groups did not differ for total dyspepsia symptom scores (table). However, fewer persons in the endoscopy group than in the test and treat group still had symptoms of . . . [Full text of this article]

Nicholas J Talley, MD, PhD

Mayo Clinic
Rochester, Minnesota, USA