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Wet wrap bandages for 4 weeks did not differ from topical ointments but increased skin infections in paediatric atopic eczema

Clinical impact ratings GP/FP/Primary care Paediatrics

Key Words: dermatitis (atopic)

The first 150 words of the full text of this article appear below.

METHODS
Design: randomised controlled trial.

Allocation: unclear concealment.^*

Blinding: blinded (scoring nurse).^*

Follow up period: 1 month.

Setting: a secondary care paediatric department at Fairfield General Hospital, Bury in Greater Manchester, UK.

Patients: 50 children 3–60 months of age who were diagnosed with moderate to severe atopic eczema according to Hanifin and Rajka criteria, and had a severity rating of moderate or severe according to the SCORing Atopic Dermatitis (SCORAD) index (score 15). Children with active skin infection at enrolment, previous allergic reactions to proposed trial treatments, or eczema predominantly on the face were excluded.

Intervention: wet wraps (n = 28) or usual care (n = 22) for 4 weeks. Wet wrap bandages were initially applied 24 hours/day over 1% hydrocortisone ointment, and if necessary, topical steroids for 1 week. Wet wraps were then applied for 12 or 24 hours/day, with hydrocortisone and emollients used during the non-wet wrap period. Usual . . . [Full text of this article]

Hywel Williams, PhD

University of Nottingham
Nottingham, UK

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Glossary
Evid. Based Med. 2006 11: 127. (in Glossary) [Extract] [Full Text] [PDF]