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Evidence-Based Medicine 2006;11:152; doi:10.1136/ebm.11.5.152
Copyright © 2006 by the BMJ Publishing Group Ltd.
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Diagnosis

Response to a 2 week continuous positive airway pressure trial accurately identified patients with obstructive sleep apnoea syndrome

Senn O, Brack T, Russi EW, et al. A continuous positive airway pressure trial as a novel approach to the diagnosis of the obstructive sleep apnea syndrome. Chest 2006;129:67–75.[Abstract/Free Full Text]

Q In patients with suspected obstructive sleep apnoea syndrome (OSA), does a self reported positive response to a 2 week continuous positive airway pressure (CPAP) trial with >2 hours of documented CPAP use per night accurately identify patients with OSA?

Clinical impact ratings GP/FP/Primary care *****{star}{star} Internal medicine *****{star}{star} Respirology ******{star}

Key Words: sleep apnoea (obstructive) • polysomnography • continuous positive airway pressure

The first 150 words of the full text of this article appear below.

METHODS
Formula Design: blinded comparison of response to a 2 week CPAP trial with polysomnography.

Formula Setting: a sleep disorder centre in Zurich, Switzerland.

Formula Patients: 76 patients (mean age 52 y, 80% men) with suspected OSA (habitual snorer, complaint of daytime sleepiness, and an Epworth sleeping scale score >=8). Exclusion criteria included a contraindication for CPAP (unstable congestive heart failure, significant lung disease, or obesity hypoventilation); significant nasal obstruction; a history of any sleep disease and CPAP treatment; or a diagnosis of an internal medical, neurological, or psychiatric disease explaining some of the symptoms.

Formula Description of test: patients were fitted with a nasal mask (Mirage, ResMed, Australia) and received 30–60 minutes of training on CPAP use. Patients were encouraged to use CPAP (DeVilbiss AutoAdjustLT or Sunrise Medical, Somerset, PA; or AutoSetT or ResMed, Redfern, Australia) with automatically adjusted mask pressure of 4–15 cm H2O every night for 2 weeks and had access . . . [Full text of this article]

Pawan Sikka, MD

VA Medical Centre & Texas A&M Health Science Center,
Temple, Texas, USA






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