Therapeutics
Long term dietary use of potassium enriched salt reduced cardiovascular death in elderly men
Chang HY, Hu YW, Yue CS, et al. Effect of potassium-enriched salt on cardiovascular mortality and medical expenses of elderly men. Am J Clin Nutr 2006;83:1289–96.
Q In elderly men, does long term use of potassium enriched salt in the diet reduce cardiovascular death?
IM/Ambulatory care Geriatrics Public health
Key Words: cardiovascular diseases • potassium chloride
| The first 150 words of the full text of this article appear below. |
Design:
cluster randomised controlled trial.
Allocation:
unclear allocation concealment.*
Blinding:
blinded (participants).*
Follow up period:
mean 31 months.
Setting:
5 kitchens in a veteran retirement home in northern Taiwan, China.
Patients:
1981 elderly men 40 to 
80 years of age (mean age 75 y) were included in the analysis. Participants with serum creatinine concentrations 3.5 mg/dl were excluded.
Intervention:
2 kitchens (n = 768) were allocated to gradually increasing concentrations of potassium enriched salt (49% sodium chloride, 49% potassium chloride, and 2% additives). Potassium enriched salt was mixed with regular salt in a 1:3 ratio for the first week, 1:1 in the second week, 3:1 in the third week, and 1:0 beyond the third week. 3 kitchens (n = 1213) were allocated to regular salt (99.6% sodium chloride and 0.4% additives) at all times.
Outcome:
cardiovascular death (due to hypertension, ischaemic heart disease, cerebrovascular disease, heart failure, or diabetes).
Patient
Yale University School of Medicine,
New Haven, Connecticut, USA
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Evid. Based Med. 2006 11: 191. (in Glossary)[Extract] [Full Text] [PDF]
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