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Evidence-Based Medicine 2006;11:185; doi:10.1136/ebm.11.6.185
Copyright © 2006 by the BMJ Publishing Group Ltd.

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Prognosis

1 year mortality after first hospital admission for heart failure was similar in patients with preserved or reduced ejection fraction

Bhatia RS, Tu JV, Lee DS, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med 2006;355:260–9.[Abstract/Free Full Text]

Q After a first hospital admission for heart failure (HF), how do the 1 year outcomes of patients with preserved ejection fraction (EF) compare with those of patients with reduced EF?

Clinical impact ratings IM/Ambulatory care ******* Internal medicine ******* Cardiology *****{star}{star}

Key Words: heart failure (congestive) • patient readmission • stroke volume

The first 150 words of the full text of this article appear below.

METHODS
Formula Design: inception cohort followed for 1 year.

Formula Setting: 103 teaching and community hospitals in Ontario, Canada.

Formula Patients: 880 patients (mean age 75 y, 66% women) with preserved EF (>50%) and 1570 patients (mean age 72 y, 63% men) with reduced EF (<40%). Patients were included if they had a first time hospital admission for HF (defined by Framingham study criteria) between 1 April 1999 and 31 March 2001 and documented evaluation of left ventricular EF at admission. Exclusion criteria were age >=105 years, transfer from another hospital, HF that developed after admission, or severe primary left sided valvular abnormality. 352 patients with borderline EF (40–50%) were omitted from the analysis.

Formula Prognostic factor: EF.

Formula Outcomes: death from any cause, hospital readmission for HF, and in-hospital complications.

MAIN RESULTS
9945 patients met the criteria for HF, but 6492 did not have EF measured or recorded and 649 were excluded because of severe left sided . . . [Full text of this article]

Ali Ahmed, MD, MPH

University of Alabama at Birmingham and VA Medical Center,
Birmingham, Alabama, USA







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