B type natriuretic peptide testing was more cost effective than conventional diagnosis in patients with acute dyspnoea

doi:10.1136/ebm.12.1.28

HOME

Author	Keyword(s)
Vol	Page
[Advanced]

Evidence-Based Medicine 2007;12:28; doi:10.1136/ebm.12.1.28
Copyright © 2007 by the BMJ Publishing Group Ltd.

This Article

	Full Text
	Full Text (PDF)
	Submit a response
	Alert me when this article is cited
	Alert me when eLetters are posted
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Add article to my folders
	Download to citation manager
	Request Permissions

Citing Articles

	Citing Articles via Google Scholar

Google Scholar

	Articles by Shetty, K.
	Articles by Garber, A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Shetty, K.
	Articles by Garber, A.

Topic Collections

	Related Article

Economics

B type natriuretic peptide testing was more cost effective than conventional diagnosis in patients with acute dyspnoea

Mueller C, Laule-Kilian K, Schindler C, et al. Cost-effectiveness of B-type natriuretic peptide testing in patients with acute dyspnea. Arch Intern Med 2006;166:1081–7.[Abstract/Free Full Text]

Q In patients who presented to the emergency department (ED) with acute dyspnoea, is a diagnostic strategy based on rapid measurement of B type natriuretic peptide (BNP) concentrations more cost effective than conventional diagnosis?

Clinical impact ratings Respirology $*$ $*$ $*$ $*$ $*$ $*$ ${star}$ Internal medicine $*$ $*$ $*$ $*$ $*$ $*$ ${star}$ Emergencymedicine $*$ $*$ $*$ $*$ $*$ ${star}$ ${star}$ Cardiology $*$ $*$ $*$ $*$ $*$ ${star}$ ${star}$

Key Words: dyspnoea • natriuretic peptide (brain)

The first 150 words of the full text of this article appear below.

METHODS
Design: cost effectiveness analysis of a randomised {allocation concealed*} ${dagger}$ ,blinded (outcome assessors*), controlled trial (B Type NatriureticPeptide for Acute Shortness of Breath Evaluation [BASEL] study)with follow up of 180 days.

Setting: ED in a university hospital in Basel, Switzerland.

Patients: 452 patients (mean age 71 y, 58% men) who presented to the EDwith acute dyspnoea. Exclusion criteria included trauma, severerenal disease, and cardiogenic shock.

Intervention: diagnostic strategy with rapid measurement of BNP concentrations(n = 225) or conventional diagnostic strategy (n = 227).

Outcomes: included all cause mortality, use of intensive care, days inhospital, and total cost of treatment.

*See glossary.

${dagger}$ Information provided by author.

MAIN RESULTS
At initial presentation, fewer patients in the BNP group thanin the conventional group were admitted to hospital (75% v 85%,p = 0.008) and required intensive care (15% v 24%, p = 0.01).The BNP group incurred . . . [Full text of this article]

Kanaka Shetty, MD, Alan Garber, MD

Veterans Affairs Palo Alto and Center for Health Policy/Primary Care, Outcomes Research, Stanford University, Stanford, California, USA

Related Article

Other articles noted
Evid. Based Med. 2007 12: 31-32. (in ) [Extract] [Full Text] [PDF]