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Key Words: evidence-based medicine

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We agree with Dr Stein’s concerns about the misapplication of EBM and thank him for helping to make sure EBM is not misunderstood. Knowledge, compassion, skill, experience, and other important clinician contributions are needed in the application of EBM if we are to do more good than harm. A recitation of recent studies is not acceptable. EBM is the integration of clinical expertise, patient circumstances and values, and the best evidence into the decision making process for patient care.