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The ABCD, California, and unified ABCD² risk scores predicted stroke within 2, 7, and 90 days after TIA

Clinical impact ratings GP/FP/Primary care Neurology Internal medicine

Key Words: cerebrovascular accident • ischaemic attack (transient)

The first 150 words of the full text of this article appear below.

METHODS
Design: 6 cohort studies: 2 derivation cohorts (California emergency department [ED] and Oxford population) and 4 independent validation cohorts (California ED, California clinic, Oxford population, and Oxford clinic).

Setting: EDs and primary care clinics in the San Francisco Bay area, California, USA and family practices and specialist clinics in Oxfordshire, UK.

Patients: 1916 patients (78% >60 y, 52% women) for derivation and 2893 patients (76% >60 y, 53% women) for validation who were diagnosed with TIA by the initial treating doctor.

Description of prediction guide: The ABCD² score was generated in the 2 original derivation cohorts by multivariate logistic regression analysis of individual risk factors from the ABCD and California scores. The risk score with the greatest area under the receiver operating characteristic (AUROC) curve for 2 day stroke was selected. The unified ABCD² score (range 0–7) was a summation of 5 independent risk predictors: Age (60 y = . . . [Full text of this article]

Graeme J Hankey, MD

Royal Perth Hospital,
Perth, Western Australia, Australia