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The evolving science of translating research evidence into clinical practice

Sutter Coast Health Center at Brookings-Harbor
Brookings, Oregon, USA

Key Words: evidence-based medicine

The first 150 words of the full text of this article appear below.

Dr Scott has provided a nice summary of the barriers to implementing research guidelines,¹ although it seems to me he misses 1 important point: the psychology of scepticism and how scepticism is learned by practitioners. I’ll illustrate what I mean by this in the field of new drugs. I think we can agree that the literature about new drugs and their use makes up a considerable proportion of any issue of a major medical journal or continuing education conference. New drugs are extensively studied, and information about their importance and potential benefits is widely disseminated to practitioners. Scepticism is often learned by doctors after the drugs have been released and lauded: Vioxx, Rezulin, Baycol, Avandia, the bisphosphonates. These were all wonder drugs on release; a couple of years later you wonder, how did this happen?

Research guidelines are tainted by association in many practitioners’ minds. Drug studies and well meaning . . . [Full text of this article]