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Evidence-Based Medicine 2007;12:123; doi:10.1136/ebm.12.4.123
Copyright © 2007 by the BMJ Publishing Group Ltd.
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Prognosis

Absolute risk of subsequent fracture was similar in women and men

Center JR, Bliuc D, Nguyen TV, et al. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA 2007;297:387–94.[Abstract/Free Full Text]

Q What is the risk of subsequent fracture after initial low impact fracture in women and men?

Clinical impact ratings GP/FP/Primary care ******{star} IM/Ambulatory care ******{star} Geriatrics *****{star}{star}

Key Words: fracture • bones

The first 150 words of the full text of this article appear below.

METHODS
Formula Design: inception cohort followed for median 16 years in women and 15 years in men (Dubbo Osteoporosis Epidemiology Study).

Formula Setting: community study in Dubbo, New South Wales, Australia.

Formula Patients: 1242 patients >=60 years of age (905 women [mean age 78 y] and 337 men [mean age 77 y] at time of incident fracture) who had an initial low impact fracture (caused by a fall from a standing height or less) between January 1989 and April 2005. Patients with skull, finger, and toe fractures or an underlying condition that could predispose to pathological fracture were excluded.

Formula Prognostic factors: smoking, alcohol, and dietary calcium intake; comorbid conditions and medications; anthropomorphic measurements; bone mineral density of the lumbar spine and femoral neck; quadriceps strength; and body sway.

Formula Outcomes: subsequent fracture.

MAIN RESULTS
Among 905 women with initial fracture, 253 had a subsequent fracture over 4076 person years (median 3.25 y) of follow up. Among 337 . . . [Full text of this article]

Sarah D Berry, MD, Douglas P Kiel, MD, MPH

Institute for Aging Research,
Hebrew SeniorLife,
Roslindale, Massachusetts, USA






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