Therapeutics
The Atkins diet led to more weight loss than the Zone diet in overweight and obese premenopausal women at 12 months
Gardner CD, Kiazand A, Alhassan S, et al. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA 2007;297:969–77.
Q In overweight or obese premenopausal women, how do the Atkins; Zone; Lifestyle, Exercise, Attitudes, Relationships, and Nutrition (LEARN); and Ornish diets compare for weight loss?
IM/Ambulatory care Obesity—surgeon Obesity—physician
Key Words: diet fads • diet (reducing) • obesity • weight loss
| The first 150 words of the full text of this article appear below. |
Design:
randomised controlled trial (The Atkins, Traditional, Ornish, Zone [A TO Z] Weight Loss Study).
Allocation:
unclear allocation concealment.*
Blinding:
blinded {data collectors, data analysts, and data safety and monitoring committee}
.*
Follow up period:
12 months.
Setting:
USA.
Patients:
311 premenopausal women 25–50 years of age (mean age 41 y, 71% white) who were overweight or obese (body mass index [BMI] 27–40 kg/m2), had stable body weight in the past 2 months, and stable medications for 
3 months. Exclusion criteria included diabetes; hypertension; heart, renal, or liver disease; cancer; hyperthyroidism; use of drugs that affect weight or energy expenditure; alcohol consumption 3 drinks/day; pregnancy; lactation; or amenorrhoea in the past year.
Intervention:
Atkins (very low carbohydrate [CARB]) (n = 77), Zone (low CARB) (n = 79), LEARN (low fat, high CARB) (n = 79), or Ornish (very high CARB) (n = 76) for 8 weeks. The LEARN programme
University of Alberta, Edmonton, Alberta, Canada
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Evid. Based Med. 2007 12: 160. (in Glossary)[Extract] [Full Text] [PDF]
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