The Atkins diet led to more weight loss than the Zone diet in overweight and obese premenopausal women at 12 months

doi:10.1136/ebm.12.5.138

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Evidence-Based Medicine 2007;12:138; doi:10.1136/ebm.12.5.138
Copyright © 2007 by the BMJ Publishing Group Ltd.

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Therapeutics

The Atkins diet led to more weight loss than the Zone diet in overweight and obese premenopausal women at 12 months

Gardner CD, Kiazand A, Alhassan S, et al. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA 2007;297:969–77.[Abstract/Free Full Text]

Q In overweight or obese premenopausal women, how do the Atkins; Zone; Lifestyle, Exercise, Attitudes, Relationships, and Nutrition (LEARN); and Ornish diets compare for weight loss?

Clinical impact ratings GP/FP/Primary care $*$ $*$ $*$ $*$ $*$ $*$ ${star}$ IM/Ambulatory care $*$ $*$ $*$ $*$ $*$ $*$ ${star}$ Obesity—surgeon $*$ $*$ $*$ $*$ $*$ $*$ ${star}$ Obesity—physician $*$ $*$ $*$ $*$ $*$ ${star}$ ${star}$

Key Words: diet fads • diet (reducing) • obesity • weight loss

The first 150 words of the full text of this article appear below.

METHODS
Design: randomised controlled trial (The Atkins, Traditional, Ornish,Zone [A TO Z] Weight Loss Study).

Allocation: unclear allocation concealment.^*

Blinding: blinded {data collectors, data analysts, and data safety andmonitoring committee}.^*

Follow up period: 12 months.

Setting: USA.

Patients: 311 premenopausal women 25–50 years of age (mean age 41y, 71% white) who were overweight or obese (body mass index[BMI] 27–40 kg/m²), had stable body weight in the past2 months, and stable medications for $>=$ 3 months. Exclusion criteriaincluded diabetes; hypertension; heart, renal, or liver disease;cancer; hyperthyroidism; use of drugs that affect weight orenergy expenditure; alcohol consumption $>=$ 3 drinks/day; pregnancy;lactation; or amenorrhoea in the past year.

Intervention: Atkins (very low carbohydrate [CARB]) (n = 77), Zone (low CARB)(n = 79), LEARN (low fat, high CARB) (n = 79), or Ornish (veryhigh CARB) (n = 76) for 8 weeks. The LEARN programme . . . [Full text of this article]

Raj Padwal, MD

University of Alberta, Edmonton, Alberta, Canada

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Glossary
Evid. Based Med. 2007 12: 160. (in Glossary) [Extract] [Full Text] [PDF]