THERAPEUTICS
Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin plus paracetamol but had fewer adverse effects in acute gout-like arthritis
In patients with acute gout-like arthritis, what is the analgesic efficacy of prednisolone plus paracetamol compared with indomethacin plus paracetamol?
| The first 150 words of the full text of this article appear below. |
Man CY, Cheung IT, Cameron PA, et al. Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute goutlike arthritis: a double-blind, randomized, controlled trial. Ann Emerg Med 2007;49:670–7.
Clinical impact ratings GP/FP/Primary care 
IM/Ambulatory care Emergency medicine Rheumatology
METHODS
Design:randomised placebo controlled trial.
Allocation:
{concealed}*.
Blinding:
blinded (patients and {healthcare providers}*).
Follow-up period:14 days.
Setting:an emergency department (ED) of a large teaching hospital in Hong Kong, China.
Patients:
90 patients >17 years of age (mean age 65 y, 82% men) with acute gouty arthritis who presented to the ED within 3 days of pain onset and had 
1 of the following: metatarsal-phalangeal joint involvement; knee or ankle joint involvement and aspirate containing crystals; or typical gouty arthritis, with either gouty tophi or previous joint aspiration confirming the diagnosis of gout. Exclusion criteria included clinical suspicion of sepsis or other joint disease, significant comorbidity, renal insufficiency, bleeding disorder,
University of California, San Diego, La Jolla, California, USA
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Pain (anaesthesia)
-
Pain (neurology)
-
Pain (palliative care)
-
Degenerative joint disease
-
Musculoskeletal syndromes
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
