AETIOLOGY
Review: increased waist circumference or waist-to-hip ratio is associated with increased risk of cardiovascular events
What is the relation between waist circumference or waist-to-hip ratio (WHR) and cardiovascular disease (CVD)?
| The first 150 words of the full text of this article appear below. |
de Koning L, Merchant AT, Pogue J, et al. Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: metaregression analysis of prospective studies. Eur Heart J 2007;28:850–6.
Clinical impact ratings GP/FP/Primary care 
IM/Ambulatory care
METHODS
Data sources:Medline (1966 to November 2006), EMBASE/Excerpta Medica (1980 to week 45, 2006), Cochrane Library (to 2006), bibliographies of relevant studies, and authors.
Study selection and assessment:
English-language prospective cohort studies or randomised controlled trials that reported relative risks (or the data to calculate them) for CVD. CVD was defined as fatal or non-fatal coronary heart disease (myocardial infarction, ischaemic heart disease, coronary artery bypass surgery, or coronary angioplasty) or stroke (ischaemic or haemorrhagic). Studies that included patients with existing metabolic risk factors (eg, diabetes) or a diagnosis or suspicion of CVD were excluded. 15 studies (n = 258 114, mean age 57 y, 64% women) met the selection criteria. Mean follow-up was 5.9 years (range 2.5–20
University of Minnesota, Minneapolis, Minnesota, USA
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