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Evidence-Based Medicine 2008;13:23; doi:10.1136/ebm.13.1.23
Copyright © 2008 by the BMJ Publishing Group Ltd.

DIAGNOSIS

Review: symptoms, signs, and lab tests have moderate accuracy for detecting appendicitis in children

The first 150 words of the full text of this article appear below.

G Bundy

Dr D G Bundy, Johns Hopkins University School of Medicine, Baltimore, MD, USA; dbundy3@jhmi.edu


REVIEW PROCESS

Aim:

how accurate are symptoms, signs, and laboratory tests for diagnosing appendicitis in children with abdominal pain?

Search methods:

Medline (to March 2007), Cochrane Library, textbooks, and reference lists.

Study selection and assessment:

fully published studies in English that evaluated the accuracy of medical history, physical examination, or basic laboratory tests for diagnosing appendicitis in children, using independent, blinded comparison with a gold standard—surgical pathological findings, clinical observation, or follow-up (level of evidence 1–3). 25 studies were included: 1 level 1 study (n = 246) of unselected children presenting to the emergency department with undifferentiated abdominal pain (appendicitis prevalence 10%) and 24 level 3 studies (n = 5590) of selected patients with suspected appendicitis (appendicitis prevalence 25–89%).

Outcomes:

sensitivity, specificity, and positive and negative likelihood ratios (LRs).


MAIN RESULTS

The table shows the results.


CONCLUSION

The most useful single feature for diagnosing appendicitis in . . . [Full text of this article]

Peter C Wyer

Columbia University, New York City, New York, USA


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