AETIOLOGY
Subclavian stenosis was associated with an increase in all-cause and cardiovascular mortality at a mean of 9.4 years
| The first 150 words of the full text of this article appear below. |
V Aboyans
Dr V Aboyans, University of California-San Diego, La Jolla, CA, USA; vaboyans@ucsd.edu
STUDY QUESTION
Is subclavian stenosis associated with increased all-cause and cardiovascular (CV) mortality?
STUDY DESIGN
cohort study including 3 cohorts.
2 vascular laboratories in San Diego, California; 3 medical centres (2 vascular laboratories, 1 general medicine clinic) in Chicago, Illinois; and a community-dwelling cohort in southern California, USA.
1778 participants (mean age 69 y, 62% men), two-thirds of whom received lower extremity arterial testing. Exclusion criteria included being bound to a wheelchair; living in a nursing home; and having dementia, amputations, or an ankle-brachial index >1.50 (in the second cohort).
subclavian stenosis (presence of brachial systolic pressure difference 
15 mm Hg).
all-cause and CV mortality at a mean of 9.4 years.
MAIN RESULTS
157 participants (8.8%) had subclavian stenosis. An association between subclavian stenosis and increased all-cause mortality was seen after adjustment for all confounding variables (table). The association with increased CV
Mount Sinai Medical Center, New York, New York, USA
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