THERAPEUTICS
Review: diet interventions, with or without exercise, promote weight loss more than advice alone
| The first 150 words of the full text of this article appear below. |
M J Franz
Ms M J Franz, Nutrition Concepts by Franz, Inc, Minneapolis, MN, USA; marionfranz@aol.com
METHODS
in overweight and obese adults, which interventions are most effective for weight loss?
PubMed (1997 to September 2004) and reference lists.
English-language, randomised controlled trials (RCTs) that evaluated weight loss interventions in overweight or obese adults and had 
1 year follow-up. 80 RCTs (n = 26 455, mean age 23–69 y, 0–100% men) met the selection criteria. At baseline, mean weight was 77–131 kg and mean body mass index was 29–43 kg/m2. The interventions included advice only (28 RCTs), exercise (6 RCTs), diet (51 RCTs), diet plus exercise (17 RCTs), meal replacements (7 RCTs), very-low-energy diet (11 RCTs), orlistat (13 RCTs), and sibutramine (7 RCTs). No RCT on bariatric surgery was found. Study duration ranged from 12 to 60 months. Overall patient follow-up at study end was 69%.
weight loss.
MAIN RESULTS
For most interventions,
University of Alberta, Edmonton, Alberta, Canada
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