THERAPEUTICS
Review: calcium supplementation, with or without vitamin D, prevents osteoporotic fractures in older people
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B Tang
Dr B Tang, University of Sydney, Penrith, New South Wales, Australia; benjamin@clubsalsa.com.au
REVIEW PROCESS
in patients 
50 years of age, does calcium supplementation, with or without vitamin D, prevent osteoporotic fractures?
Medline, EMBASE/Excerpta Medica, Current Contents, CINAHL, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews (all to January 2007); clinical trials repositories; resource web sites; conference abstracts; review articles; and bibliographies of primary studies.
published or unpublished randomised controlled trials (RCTs) in any language that compared the effects of calcium, with or without vitamin D, with placebo on fractures or bone mineral density (BMD) in patients 50 years of age. Exclusion criteria were use of dietary calcium as an intervention, use of calcium as part of a nutritional supplementation regimen or combined with other treatment, secondary osteoporosis, and use of vitamin D without calcium. 29 studies met the selection
Multidisciplinary Osteoporosis Program, Women's College Hospital, Toronto, Ontario, Canada
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