DIAGNOSIS
Random urine protein:creatinine ratio was an accurate method for diagnosing proteinuria in pregnant women with hypertension
| The first 150 words of the full text of this article appear below. |
Dr A Leaños-Miranda
Correspondence to: Dr A Leaños-Miranda, Hospital de Ginecología y Obstetricia "Luis Castelazo Ayala", Mexico City, Mexico; alfredolm@yahoo.com
STUDY QUESTION
In pregnant women with hypertension, is measurement of protein:creatinine ratio (PCR) in a single random urine sample an accurate method for diagnosing proteinuria compared with 24-hour urine collection?
STUDY DESIGN
prospective cohort study.
hospital in Mexico.
927 pregnant women (mean age 29 y) admitted to hospital at 
20 gestational weeks (mean 33 wk) with new onset hypertension (87% of women), chronic hypertension with suspected pre-eclampsia (6%), or normal blood pressure (7%).
PCR measured in a single random daytime urine sample (not first morning void).
protein measured in a 24-hour urine collection. A value 300 mg/24 h was considered diagnostic of significant proteinuria. A value 2 g/24 h indicated severe proteinuria.
sensitivity, specificity, and positive (+LR) and negative (–LR) likelihood ratios.
MAIN RESULTS
Protein excretion was 300 mg/24 h in 30% of women and 2
King’s College London, London, UK
St Thomas’ Hospital, London, UK
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