DIAGNOSIS
Albumin:creatinine ratio using an automated analyser was accurate for diagnosing proteinuria in pregnancy
| The first 150 words of the full text of this article appear below. |
P M Kyle
Professor P M Kyle, University of Otago, Christchurch, New Zealand; pippa.kyle@otago.ac.nz
STUDY QUESTION
In high-risk pregnant women, how accurate for diagnosing proteinuria are albumin:creatinine ratio (A/Cr) tested on-site using an automated analyser, protein:creatinine ratio (P/Cr) tested in the laboratory, and automated dipstick analysis used on-site compared with 24-hour urine collection?
STUDY DESIGN
prospective cohort study.
high-risk antenatal clinic in a university hospital in New Zealand.
140 pregnant women (10 women were included twice) at >20 gestational weeks (median 34 wk). The women provided a midstream urine specimen for automated dipstick analysis; those with a 
1+ result for new-onset proteinuria were invited to participate (n = 100), along with a selection of women with a negative or trace proteinuria result (n = 50). Women with culture-positive urinary tract infection, proteinuric renal disease, or diabetes with an abnormal first-trimester A/Cr were excluded.
automated dipstick analysis done on-site (cutpoint 1+), A/Cr done on-site (5
BC Women's Hospital and University of British Columbia, Vancouver, British Columbia, Canada
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