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Evidence-Based Medicine 2008;13:120; doi:10.1136/ebm.13.4.120
Copyright © 2008 by the BMJ Publishing Group Ltd.

PROGNOSIS

Age, sex, and functional impairment predicted risk of mortality in incident dementia at 14 years

The first 150 words of the full text of this article appear below.

C Brayne

Dr C Brayne, University of Cambridge, Cambridge, UK; carol.brayne@medschl.cam.ac.uk


STUDY QUESTION

In patients with incident dementia, what is the association between various prognostic factors and risk of mortality?


STUDY DESIGN

Design:

prospective cohort study followed for 14 years.

Setting:

2 rural and 3 urban centres in England and Wales, UK.

Patients:

inception cohort of 438 patients >65 years of age (median age 84 y) who were diagnosed with dementia based on a geriatric mental state examination algorithm. People who had prevalent dementia during entry into the cohort or whose onset of dementia could not be estimated were excluded.

Prognostic factors:

age at onset of dementia, sex, marital status, accommodation type (community or institution), education level (<=9 y, 10–11 y, or >=12 y), social class (professional, managerial and technical, skilled non-manual and manual, partly skilled, or unskilled manual), functional status (least, middle, or most impairment on the Blessed Dementia Scale), score on the Mini-Mental State Examination (MMSE) . . . [Full text of this article]

David W Molloy

St. Peter's Centre for Studies on Aging Hamilton, Ontario, Canada


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