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Evidence-Based Medicine 2008;13:180; doi:10.1136/ebm.13.6.180
Copyright © 2008 by the BMJ Publishing Group Ltd.

THERAPEUTICS

Placebo acupuncture improved symptoms and quality of life in irritable bowel syndrome

The first 150 words of the full text of this article appear below.

T J Kaptchuk

Dr T J Kaptchuk, Harvard Medical School, Boston, MA, USA; ted_kaptchuk@hms.harvard.edu


STUDY DESIGN

Design:

randomised controlled trial (RCT).

Allocation:

concealed.*

Blinding:

blinded (patients, outcome assessors, {data collectors, and data analysts}{dagger}).*


STUDY QUESTION

Setting:

academic medical centre {in Boston, MA, USA}{dagger}.

Patients:

262 patients (mean age 39 y, 76% women) who had irritable bowel syndrome (IBS) and a Symptom Severity Scale score >=150. Exclusion criteria included loss of >10% of body weight, fever, blood in stool, family history of colon cancer, inflammatory bowel disease, and previous acupuncture.

Intervention:

augmented placebo (n = 87), limited placebo (n = 88), or wait list (n = 87). Placebo treatments were sham acupuncture (6–8 dummy needles twice/wk). The augmented-placebo group had a defined positive patient–doctor relationship (25 min of warmth, active listening, thoughtful silence, communication of confidence, and positive expectation) whereas the limited-placebo group had minimal interaction with the doctor (<5 min).

Outcomes:

included Global Improvement Scale (GIS), symptom relief, and . . . [Full text of this article]

Nicholas J Talley

Mayo Clinic, Jacksonville, Florida, USA


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