THERAPEUTICS
In high-risk adolescents, cognitive-behavioural therapy reduced depression at 6 months more than assessment alone but did not differ from bibliotherapy or supportive-expressive therapy
| The first 150 words of the full text of this article appear below. |
E Stice
Dr E Stice, Oregon Research Institute, Eugene, OR, USA; estice@ori.org
STUDY DESIGN
randomised controlled trial.
{unconcealed}*.
blinded (outcome assessors).
STUDY QUESTION
6 high schools in the USA.
341 students 14–19 years of age (mean age 16 y, 56% women) who scored 
20 on the Center for Epidemiologic Studies—Depression scale and did not meet criteria for major depression.
brief cognitive–behavioural group therapy (CBT, n = 89) or supportive-expressive group therapy (SET, n = 88), both given in 6 weekly 1-hour sessions; cognitive-behavioural bibliotherapy (CBB, n = 80); or assessment–only control (AC, n = 84).
included symptoms and diagnosis of major depression, assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (16-item scale), social adjustment, assessed using the adapted Social Adjustment Scale Self-Report for Youth (17-item scale), and substance use (10–item scale).
6 months.
93% at 6 months (100% in intention-to-treat analysis).
MAIN RESULTS
Groups differed for depression symptoms (p<0.001), social adjustment (p
Yale University, New Haven, Connecticut, USA
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Child and adolescent psychiatry
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Mood disorders (including depression)
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Psychotherapy
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Clinical trials (epidemiology)
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