DIAGNOSIS
Clinical diagnosis of vaginitis was moderately accurate in symptomatic women
| The first 150 words of the full text of this article appear below. |
STUDY QUESTION
In women with vulvovaginal symptoms, how accurate is a clinical diagnosis of vaginitis?
STUDY DESIGN
blinded comparison of clinical diagnosis with DNA probe analysis.
4 US military medical clinics.
535 women 18–50 years of age (mean age 26 y) who presented with vulvovaginal symptoms (51% with abnormal discharge, 33% with itching/irritation, 10% with malodour, and 4% with vulvar burning). Women who were menstruating or had had coitus in <24 hours were excluded.
standard clinical diagnosis by a nurse practitioner consisting of history; physical examination; and pH determination, amines (whiff) test, and wet-prep microscopy of vaginal secretions.
DNA probe analysis on vaginal secretions for Gardnerella vaginalis, Trichomonas vaginalis, and candida species.
sensitivity, specificity, accuracy, and positive and negative likelihood ratios of clinical diagnosis for each of the 3 types of vaginitis.
MAIN RESULTS
By DNA probe analysis, 42% of women had bacterial vaginosis, 14% had candidiasis vaginitis, 1.5% had trichomoniasis vaginalis, 16% had
University of Missouri-Kansas City Kansas City, Missouri, USA
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