THERAPEUTICS
Review: low glycaemic-index diets reduce HbA1c more than high glycaemic-index diets in diabetes mellitus
| The first 150 words of the full text of this article appear below. |
QUESTION
In patients with diabetes mellitus, do low glycaemic-index (GI) or low glycaemic-load (GL) diets improve glycaemic control?
REVIEW SCOPE
Included studies were randomised controlled trials (RCTs) that compared a low GI or low GL diet with a higher GI or higher GL diet for
4 weeks in patients with diabetes mellitus according to validated and specified criteria. The dietary intervention had to be explicit and supervised or documented.
Outcomes were glycaemic control (glycated haemoglobin [HbA1c] for studies >6 wks; fructosamine or glycated serum albumin [GSA] for studies
6 wks) and adverse effects.
REVIEW METHODS
Cochrane Library, Medline, EMBASE/Excerpta Medica, and CINAHL (all to June 2008); and reference lists were searched. 11 RCTs (n = 402; mean age range 10–63 y) were included. Sample duration ranged from 6 patients in a crossover RCT to 104 in a parallel RCT. Intervention duration ranged from 4 weeks to 1 year. Data were pooled using a
University of Florida, Gainesville, Florida, USA
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