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Evidence-Based Medicine 2009;14:124; doi:10.1136/ebm.14.4.124
Copyright © 2009 by the BMJ Publishing Group Ltd.

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The first 150 words of the full text of this article appear below.

Anthony Harnden, MB ChB, MSc, FRCGP, FRCPCH

University of Oxford, Oxford, UK


Isaacs D. Evidence-based pediatric infectious diseases. West Sussex, UK: Wiley-Blackwell, 2007.

Perhaps the title should be evidence-based management of paediatric infectious diseases, which is the essence of this competent book edited by an ensemble of experienced international authors familiar with the methods of evidence-based medicine. The editorial team forms a nice blend of disciplines: clinical paediatric infectious disease, clinical epidemiology, microbiology, and teaching, and the resulting flavour of the text is highly palatable.

There is a systematic attempt to cite high-quality evidence when available, although it is clear that for many infections there is a void of evidence in the literature. A significant problem is that many paediatric drug preparation trials have only been conducted in adults. As the authors acknowledge, there are also difficulties in applying adult evidence to children with a condition like appendicitis where the diagnostic issues are often very different to those of adults. It . . . [Full text of this article]


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