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Evidence-Based Medicine 2009;14:155; doi:10.1136/ebm.14.5.155
Copyright © 2009 by the BMJ Publishing Group Ltd.

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Clinical prediction guide

A dipstick clinical prediction rule modestly improved diagnostic precision in women with suspected urinary tract infection

The first 150 words of the full text of this article appear below.

Study question

In women with suspected urinary tract infection (UTI), do clinical prediction rules based on clinical information or dipstick results improve diagnostic precision?

Study design

Design:

2 prospective cohort studies to derive and validate 2 clinical prediction rules.

Setting:

67 primary care practices in the south of England, UK.

Patients:

408 women in the derivation cohort and 434 women in the validation cohort who were 17–70 years of age and had suspected UTI. Exclusion criteria were pregnancy, severe mental problems, and high probability of an alternate diagnosis.

Description of prediction guides:

dipstick rule: a positive test was the presence of either (i) nitrite or (ii) the combination of blood and leucocytes. Clinical rule: a positive test was the presence of >=2 of cloudy urine, urine with an offensive smell, moderately bad dysuria, and moderately bad nocturia.

Outcomes:

UTI, determined by evidence of bacterial growth (using European urinalysis guidelines, >=103 colony-forming units/ml for Escherichia coli) on . . . [Full text of this article]

Les Toop, Dee Mangin (Richards)

University of Otago, Christchurch, New Zealand


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