Context

Cervical intraepithelial neoplasia (CIN) is a common complication in women of reproductive age. Treatment options include excisional treatments, such as cold knife conisation, loop electrosurgical excision procedure, large loop excision of the transformation zone (LLETZ) and laser conisation; and ablative treatments, including cryotherapy, laser ablation, cold coagulation and diathermy. These treatments may have an impact on subsequent pregnancy outcomes. The meta-analysis by Bruinsma and Quinn evaluates the effect of the type of comparison group on the association between treatment for CIN and subsequent preterm birth <37 weeks gestation.