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Evidence-Based Medicine 2000;5:38; doi:10.1136/ebm.5.2.38
Copyright © 2000 by the BMJ Publishing Group Ltd.
Evidence-Based Medicine 2000; 5:38
© 2000 Evidence-Based Medicine

Incorporating allocation concealment and blinding in randomised controlled trials

R Brian Haynes, MD, PhD

Editor

While we are happy to take credit for incorporating more information on blinding and concealment in our abstracts, the credit for stimulating us to do so belongs elsewhere. First, Ken Schulz and others have shown us that randomisation, blinding, and concealment of allocation make a difference to the accuracy of trial reports. Second, Phillip Devereaux and others have taken us to task for failing to report these important features of clinical trials. Readers will find that abstracts of trials now include whether the randomisation was concealed from those responsible for entering patients into trials and who was blinded to treatment allocation during the trial. This information will be provided under the "Design" heading in abstracts whenever it is possible to obtain it from the study report or, failing that, directly from the investigators.

Unfortunately, our experience to date shows that it is not always possible to acquire an unequivocal answer . . . [Full text of this article]


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  • Chalmers, I. (2001). Comparing like with like: some historical milestones in the evolution of methods to create unbiased comparison groups in therapeutic experiments. Int J Epidemiol 30: 1156-1164 [Abstract] [Full Text]  

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