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Review: injection treatment is not better than placebo for relieving pain in benign chronic low back pain

Data sources
Studies were identified by searching Medline (1966–96), EMBASE/Excerpta Medica (to 1996), and bibliographies of relevant studies.

Study selection
Studies published as full reports in English, French, German, Dutch, and Nordic languages were selected if they were randomised controlled trials (RCTs) of injection treatment for pain relief in patients who had benign chronic low back pain for 1 month.

Data extraction
Data were extracted on study methods, participants, interventions, outcome measures, timing of outcome measures, side effects, and main results. The primary outcome measure was the proportion of patients with pain relief. The quality of study methods was assessed (maximum score, 100 points).

Main results
21 RCTs met the selection criteria; 19 RCTs involving 1051 patients provided data on the proportion of patients with pain relief. Quality scores ranged from 23 to 83 points (mean 45 points). 11 RCTs compared injection treatment with placebo, and 10 RCTs compared different types of injection treatment. 1 RCT compared facet . . . [Full text of this article]

Robert Badgett, MD

University of Texas Health Science Center at San Antonio San Antonio, Texas, USA