HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Uhari, M. Search for Related Content PubMed Articles by Uhari, M.

Review: Lactobacillus is safe and effective for treating children with acute infectious diarrhoea

The first 150 words of the full text of this article appear below.

Data sources
Studies were identified by searching Medline, EMBASE/Excerpta Medica, the Cochrane Controlled Trials Register, DARE, and CINAHL from 1966 to 2000, and AMED, MANTIS, the Complementary and Alternative Medicine Citation Index, and AltHealthWatch from 1985–2000. Search terms used were diarrhoea, gastroenteritis, or rotavirus combined with competitive inhibition, Lactobacillus, probiotic, yogurt, or yoghurt. Bibliographies of relevant papers were scanned, and key investigators were contacted.

Study selection
Randomised controlled trials (RCTs) were selected if they involved Lactobacillus treatment of ID in children, clinical outcomes were reported, the treatment group received Lactobacillus and the control group received a suitable placebo, the Lactobacillus and control groups were indistinguishable, and data assessors were blinded to participant treatment group. Studies in which patients had recently received antibiotics were excluded.

Data extraction
Data were extracted on study and participant characteristics, strain of Lactobacillus, definition of diarrhoea, infectious pathogens, adverse effects, and such outcomes as duration and frequency of diarrhoea.

Main results
26 . . . [Full text of this article]

Matti Uhari, MD PhD

University of Oulu
Oulu, Finland