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Evidence-Based Medicine 2003; 8:31
© 2003 BMJ Publishing Group


Prognosis

Functional neurological deficit but not epilepsy alone increased the risk of death in childhood epilepsy

Camfield CS, Camfield PR, Veugelers PJ.Death in children with epilepsy: a population-based study.Lancet 2002 ;359:1891–5[CrossRef][Medline]

QUESTION: What are the risk factors for, and frequency of, all cause mortality in children with epilepsy?

Key Words: child • epilepsy

The first 150 words of the full text of this article appear below.

Design
Inception cohort of children who developed epilepsy between 1977 and 1985 and were followed up for <=22.5 years.

Setting
Nova Scotia, Canada.

Patients
692 children (50% girls) who developed epilepsy (>=2 unprovoked seizures) between 1977 and 1985 in Nova Scotia. Exclusion criteria included acute provoking factors for seizures, evidence of progressive neurological disease, and children who had had only neonatal seizures, unless the seizures had stopped by the time of neonatal discharge from hospital and later recurred without provocation.

Assessment of prognostic factors
In 1999, names and birth dates of the cohort were linked to the Nova Scotia provincial death and marriage registries (Division of Vital Statistics). For women >15 years of age, the marriage registry was checked to ascertain whether the names had been changed by marriage, and the marriage name was also checked against the death registry. Death certificates, necropsy reports, and physician records of children who had died were examined and families . . . [Full text of this article]

Paul O’Connor, MD

St Michael’s Hospital
Toronto, Ontario, Canada







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