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Therapeutics |
Key Words: diabetes mellitus (insulin-dependent) insulin diet patient education
| The first 150 words of the full text of this article appear below. |
Design
Randomised (allocation concealed*), unblinded,* wait list controlled trial with follow up at 6 months (Dose Adjustment for Normal Eating [DAFNE]).
Setting
3 hospital diabetes clinics in Sheffield, Northumbria, and London, UK.
Patients
169 patients >18 years of age with clinical features of type 1 diabetes, moderate or poor glycaemic control (glycated haemoglobin [HbA1c] 7.512%), and duration of diabetes >2 years without advanced complications. Exclusion criteria were inability to understand English, severe psychiatric illness, pregnancy, and unawareness of hypoglycaemia. 136 patients (80%) completed baseline and 6 month assessments (mean age 40 y, 56% women).
Intervention
84 patients were allocated to the intervention, which comprised a 5 day skills course delivered by 23 educators (diabetes specialist nurses or dieticians) to groups of 68 participants in each centre. Patients were taught the skills to adjust their insulin by matching it to the desired carbohydrate intake at each meal (rather than adjusting the timing and
Arthur T Evans, MD, MPH, Rasa Kazlauskaite, MD
Cook County Hospital and Rush Medical College
Chicago, Illinois, USA
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