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Therapeutics |
Key Words: abdominal pain famotidine pain measurement pizotyline behaviour therapy plant oils
| The first 150 words of the full text of this article appear below. |
Data sources
Studies were identified by searching Medline (1966 to 2001), the Cochrane Clinical Trial registry, the Cochrane Database of Systematic Reviews, AMED, PsycINFO, and PubMed via the National Center for Complementary and Alternative Medicine; and by reviewing bibliographies of relevant articles using terms including recurrent abdominal pain, functional abdominal pain, irritable bowel syndrome, children, and alternative therapies.
Study selection
English language randomised controlled trials (RCTs) were selected if they were done on children aged
18 years with a diagnosis of RAP. Studies not on functional gastrointestinal disorders, and those lacking a control group were excluded.
Data extraction
Data were extracted on participants characteristics and heterogeneity, study quality and design, interventions, outcomes, and a studys adherence to the standardised case definition of RAP (
3 episodes of abdominal pain occurring over
3 mo and severe enough to interfere with normal activities).
Main results
10 trials met the inclusion criteria and all studies stated that they were blinded. 2
Klaus-Michael Keller, MD, Professor Dr
Deutsche Klinik fur Diagnostik
Aukammallee, Wiesbaden, Germany
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