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Evidence-Based Medicine 2004; 9:110
© 2004 BMJ Publishing Group Ltd.


Therapeutics

Review: counselling, pharmacotherapy, and surgery help obese adults lose weight

McTigue KM, Harris R, Hemphill B, et al. Screening and interventions for obesity in adults: summary of the evidence for the U S Preventive Services Task Force. Ann Intern Med 2003;139:933–49.[Abstract/Free Full Text]

Q In adults, is obesity screening and treatment effective?

Clinical impact ratings GP/FP/Primary care *****{star}{star} IM/Ambulatory care *****{star}{star} Cardiology *****{star}{star} Endocrine ****{star}{star}{star} Geriatrics ******{star}

Key Words: behaviour therapy • counselling • obesity • orlistat • sibutramine • surgery

The first 150 words of the full text of this article appear below.

METHODS
Data sources: Medline, the Cochrane Library, and systematic reviews from the US, Canada, and the UK.

Study selection and assessment: randomised controlled trials (RCTs) or systematic reviews of screening and treatment for obesity. Drug treatment studies had to have >=6 months of follow up; all other treatments had to have >=12 months of follow up. Study quality was assessed using the US Preventive Services Task Force criteria.

Outcome: weight loss.

MAIN RESULTS
No RCTs evaluated the efficacy of obesity screening. Counselling and behavioural interventions. 3 systematic reviews showed that behavioural interventions promoting exercise and/or dietary change achieved small weight reductions (US: 29 RCTs, mean weight change over controls –3.3 kg, range –8.8 to 1.9 at >=1 y) (UK: 24 RCTs, mean weight change over controls –3.0, range –10.6 to 1.4 at 12–60 mo) (Canada: 6 RCTs, mean weight change over controls –2.1, range –4.5 to –0.2 at 24–84 mo). Of 11 . . . [Full text of this article]

James D Douketis, MD, FRCP(C)

St Joseph’s Hospital
Hamilton, Ontario, Canada







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