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Evidence-Based Medicine 2004; 9:147
© 2004 BMJ Publishing Group Ltd.


Therapeutics

CBT added to tapering helped patients with chronic insomnia discontinue benzodiazepine use

Morin CM, Bastien C, Guay B, et al. Randomized clinical trial of supervised tapering and cognitive behavior therapy to facilitate benzodiazepine discontinuation in older adults with chronic insomnia. Am J Psychiatry 2004;161:332–42.[Abstract/Free Full Text]

Q In older patients with both chronic insomnia and long term use of benzodiazepines (BDPs), is cognitive behavioural therapy (CBT) plus supervised medical tapering (SMT) (combined therapy [CT]) more effective than CBT or SMT alone for discontinuing BDPs?

Clinical impact ratings GP/FP/Primary care ******{star} Mental Health *****{star}{star}

Key Words: benzodiazepines • cognitive therapy • sleep initiation and maintenance disorders

The first 150 words of the full text of this article appear below.

METHODS
{ebmflochart.f1}Design: randomised controlled trial.

{ebmclsdenvelop.f1}Allocation: {allocation concealed*}.{dagger}

{ebmhalfeye.f1}Blinding: blinded (technician who scored polysomnography sleep stages).*

{ebmhourglass.f1}Follow up period: 12 months

{ebmglobe.f1}Setting: a research based sleep clinic in a university hospital in Sainte-Foy, Québec, Canada.

{ebmpatient.f1}Patients: 76 patients >=55 years of age (mean age 63 y, 50% women) with chronic insomnia (for >=6 months), impaired daytime functioning or mood disturbances, and benzodiazepine use (on >50% of nights) for >=3 months. Exclusion criteria included medical or psychiatric disorders known to cause insomnia, sleep apnoea, periodic limb movements during sleep and other psychiatric disorders or cognitive impairment.

{ebmrx.f1}Intervention: 10 weeks of CT (n = 27), CBT (n = 24), or SMT (n = 25). SMT in both CT and SMT alone groups aimed for dosage reductions of 25% at 2 week intervals until the lowest available dose of the BDP was reached. CBT (10 ninety minute weekly sessions) was designed to reinforce . . . [Full text of this article]

Patrick G O’Malley, MD, MPH, FACP

Walter Reed Army Medical Center
Washington, DC, USA







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