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THERAPEUTICS
Vertigan AE, Theodoros DG, Gibson PG, et al. Efficacy of speech pathology management for chronic cough: a randomised placebo controlled trial of treatment efficacy. Thorax 2006;61:10659.
GP/FP/Primary care 





Respirology 





IM/Ambulatory care 





Lavery LA, Higgins KR, Lanctot DR, et al. Preventing diabetic foot ulcer recurrence in high-risk patients: use of temperature monitoring as a self-assessment tool. Diabetes Care 2007;30:1420.
Endocrine 





Surgerygeneral 





Surgeryorthopaedics 





IM/Ambulatory care 





Steures P, van der Steeg JW, Hompes PG, et al. Intrauterine insemination with controlled ovarian hyperstimulation versus expectant management for couples with unexplained subfertility and an intermediate prognosis: a randomised clinical trial. Lancet 2006;368:21621.[CrossRef][Medline]
Obstetrics 





GP/FP/Obstetrics 





Cumming RG, Ivers R, Clemson L, et al. Improving vision to prevent falls in frail older people: a randomized trial. J Am Geriatr Soc 2007;55:17581.[CrossRef][Medline]
GP/FP/Primary care 





Geriatrics 





Sijbrandij M, Olff M, Reitsma JB, et al. Treatment of acute posttraumatic stress disorder with brief cognitive behavioral therapy: a randomized controlled trial. Am J Psychiatry 2007;164:8290.
GP/FP/Primary care 





Psychiatry 





GP/FP/Mental health 





Tran T, Lowry AM, El-Serag HB. Meta-analysis: the efficacy of over-the-counter gastro-oesophageal reflux disease therapies. Aliment Pharmacol Ther 2007;25:14353.[Medline]
GP/FP/Primary care 





IM/Ambulatory care 





Gastroenterology 





Jones MH, Amendola AS. Acute treatment of inversion ankle sprains: immobilization versus functional treatment. Clin Orthop Relat Res 2007;455:16972.[CrossRef][Medline]
GP/FP/Primary care 





Emergency medicine 





Physical medicine & rehabilitation 





Draelos ZD, Carter E, Maloney JM, et al. Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris. J Am Acad Dermatol 2007;56:439.e110.[Medline]
GP/FP/Primary care 





Dermatology 





Alkhenizan AH, Alswes MA. The role of renin blockers in the prevention of diabetes. Saudi Med J 2007;28:915.[Medline]
GP/FP/Primary care 





IM/Ambulatory care 





Endocrine 





Broe KE, Chen TC, Weinberg J, et al. A higher dose of vitamin D reduces the risk of falls in nursing home residents: a randomized, multiple-dose study. J Am Geriatric Soc 2007;55:2349.[CrossRef][Medline]
GP/FP/Primary care 





Geriatrics 





Miller MD, Marty MA, Broadwin R, et al. The association between exposure to environmental tobacco smoke and breast cancer: a review by the California Environmental Protection Agency. Prev Med 2007:44:93106.[CrossRef][Medline]
GP/FP/Primary care 





Occupational & environmental health 





Public health 





Oncology 





Nasr IA, Bouzamondo A, Hulot JS, et al. Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: a meta-analysis. Eur Heart J 2007;28:457462.
IM/Ambulatory care 





Cardiology 





Kirwan J, Bijlsma J, Boers M, et al. Effects of glucocorticoids on radiological progression in rheumatoid arthritis. Cochrane Database Sys Rev 2007;(1):CD006356.
IM/Ambulatory care 





Neurology 





Ray D, Goswami R, Banerjee U, et al. Prevalence of Candida glabrata and its response to boric acid vaginal suppositories in comparison with oral fluconazole in patients with diabetes and vulvovaginal candidiasis. Diabetes Care 2007;30:3127.
Endocrine 





Gynaecology 





Kennard B, Silva S, Vitiello B, et al. Remission and residual symptoms after short-term treatment in the Treatment of Adolescents with Depression Study (TADS). J Am Acad Child Adolesc Psychiatry 2006;45:140411.[CrossRef][Medline]
GP/FP/Mental health 





Psychiatry 





Murata M, Hasegawa K, Kanazawa I, et al. Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study. Neurology 2007;68:4550.
Neurology 





Davis AR, Hendlish SK, Westhoff C, et al. Bleeding patterns after misoprostol vs surgical treatment of early pregnancy failure: results from a randomized trial. Am J Obstet Gynecol 2007;196:31.e17.[CrossRef][Medline]
GP/FP/Obstetrics 





Gynaecology 





Obstetrics 





Gupta P, Ray M, Dua T, et al. Multimicronutrient supplementation for undernourished pregnant women and the birth size of their offspring: a double-blind, randomized, placebo-controlled trial. Arch Pediatr Adolesc Med 2007;161:5864.
GP/FP/Obstetrics 





Paediatrics (general) 





Obstetrics 





Smith GN, Walker MC, Ohlsson A, et al. Randomized double-blind placebo-controlled trial of transdermal nitroglycerin for preterm labor. Am J Obstet Gynecol 2007;196:37.e18.[Medline]
GP/FP/Obstetrics 





Obstetrics 





Fernando R, Sultan AH, Dettle C, et al. Methods of repair for obstetric anal sphincter injury. Cochrane Database Syst Rev 2006;(3):CD002866.[Medline]
GP/FP/Obstetrics 





Gynaecology 





Obstetrics 





Morton DL, Thompson JF, Cochran AJ, et al. Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med 2006;355:130717.
Oncology 





Dermatology 





Surgeryoncology 





Smith I, Procter M, Gelber RD, et al. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet 2007;369:2936.[CrossRef][Medline]
Oncology 





Osterman H, Seitsalo S, Karppinen J, et al. Effectiveness of microdiscectomy for lumbar disc herniation: a randomized controlled trial with 2 years of follow-up. Spine 2006;31:240914.[CrossRef][Medline]
Physical medicine & rehabilitation 





Surgeryorthopaedics 





Rheumatology 





Wakai A, OSullivan R, McCabe G. Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults. Cochrane Database Syst Rev 2007;(1):CD004479.[Medline]
Respirology 





Surgerythoracic 





Jakobsen BW, Johannsen HV, Suder P, et al. Primary repair versus conservative treatment of first-time traumatic anterior dislocation of the shoulder: a randomized study with 10-year follow-up. Arthroscopy 2007;23:11823.[Medline]
Surgeryorthopaedics 





Addolorato G, Leggio L, Abenavoli L, et al. Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam. Am J Med 2006;119:276.e138.
GP/FP/Primary care 





Psychiatry 





Internal medicine 





Wang TJ, Belza B, Elaine Thompson F, et al. Effects of aquatic exercise on flexibility, strength and aerobic fitness in adults with osteoarthritis of the hip or knee. J Adv Nurs 2007;57:14152.[CrossRef][Medline]
GP/FP/Primary care 





Physical medicine & rehabilitation 





Rheumatology 





Segal JB, Streiff MB, Hoffman LV, et al. Management of venous thromboembolism: a systematic review for a practice guideline. Ann Intern Med 2007;146:21122.
GP/FP/Primary care 





Internal medicine 





Respirology 





Haematology 





Reed GL, Enright RD. The effects of forgiveness therapy on depression, anxiety, and posttraumatic stress for women after spousal emotional abuse. J Consult Clin Psychol 2006;74:9209.[CrossRef][Medline]
GP/FP/Mental health 





DIAGNOSIS
Zuckerbrot RA, Jensen PS. Improving recognition of adolescent depression in primary care. Arch Pediatr Adolesc Med 2006;160:694704.
Paediatrics (general) 





GP/FP/Mental health 





Psychiatry 





Geifman-Holtzman O, Grotegut CA, Gaughan JP. Diagnostic accuracy of noninvasive fetal Rh genotyping from maternal blooda meta-analysis. Am J Obstet Gynecol 2006;195:116373.[CrossRef][Medline]
GP/FP/Obstetrics 





Paediatrics (general) 





Obstetrics 





Haematology 





Ramsey DJ, Smithard DG, Kalra L. Can pulse oximetry or a bedside swallowing assessment be used to detect aspiration after stroke? Stroke 2006;37:29848.
Internal medicine 





Neurology 





PROGNOSIS
Nichols GA, Hillier TA, Brown JB. Progression from newly acquired impaired fasting glucose to type 2 diabetes. Diabetes Care 2007;30:22833.
GP/FP/Primary care 





Endocrine 





IM/Ambulatory care 





Thomas DB, Franceschini N, Hogan SL, et al. Clinical and pathologic characteristics of focal segmental glomerulosclerosis pathologic variants. Kidney Int 2006;69:9206.[CrossRef][Medline]
Nephrology 





AETIOLOGY
Van Biesen W, De Bacquer D, Verbeke F, et al. The glomerular filtration rate in an apparently healthy population and its relation with cardiovascular mortality during 10 years. Eur Heart J 2007;28:47883.
GP/FP/Primary care 





Cardiology 





IM/Ambulatory care 





Cohen HW, Hailpern SM, Fang J, et al. Sodium intake and mortality in the NHANES II follow-up study. Am J Med 2006;119:275.e714.
GP/FP/Primary care 





IM/Ambulatory care 





Cardiology 





Nephrology 





Suissa S, Hutchinson T, Brophy JM, et al. ACE-inhibitor use and the long-term risk of renal failure in diabetes. Kidney 2006;69:9139.[CrossRef]
Cardiology 





Endocrine 





IM/Ambulatory 





Nephrology 





White HD, Gruber M, Feyzi J, et al. Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: results from SPORTIF III and V. Arch Intern Med 2007;167:23945.[CrossRef][Medline]
GP/FP/Primary care 





IM/Ambulatory care 





Cardiology 





Haematology 





CLINICAL PREDICTION GUIDE
Ridker PM, Buring JE, Rifai N, et al. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA 2007;297:6119.
GP/FP/Primary care 





IM/Ambulatory care 





Neurology 





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