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THERAPEUTICS
Hyams J, Crandall W, Kugathasan S, et al. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohns disease in children. Gastroenterology 2007;132:863–73.[CrossRef][Medline]
Gastroenterology 





Block GA, Raggi P, Bellasi A, et al. Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int 2007;71:438–41.[CrossRef][Medline]
Nephrology 





Cepeda MS, Camargo F, Zea C, et al. Tramadol for osteoarthritis: a systematic review and metaanalysis. J Rheumatol 2007;34:543–55.[Medline]
GP/FP/Primary care 





Rheumatology 





Deedwania P, Stone PH, Bairey Merz CN, et al. Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE). Circulation 2007;115:700–7.
GP/FP/Primary care 





Cardiology 





Geriatrics 





Heiman JR, Talley DR, Bailen JL, et al. Sexual function and satisfaction in heterosexual couples when men are administered sildenafil citrate (Viagra) for erectile dysfunction: a multicentre, randomised, double-blind, placebo-controlled trial. BJOG 2007;114:437–47.[CrossRef][Medline]
GP/FP/Primary care 





Walters EH, Gibson PG, Lasserson TJ, et al. Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid. Cochrane Database Syst Rev 2007;(1):CD001385.[Medline]
GP/FP/Primary care 





Watkins CL, Auton MF, Deans CF, et al. Motivational interviewing early after acute stroke: a randomized, controlled trial. Stroke 2007;38:1004–9.
Internal medicine 





Physical medicine & rehabilitation 





Psychiatry/Mental health 





Cox G, Thomson NC, Rubin AS, et al. Asthma control during the year after bronchial thermoplasty. N Engl J Med 2007;356:1327–37.
Allergy & immunology 





Respirology 





Hsia J, Heiss G, Ren H, et al. Calcium/vitamin D supplementation and cardiovascular events. Circulation 2007;115:846–54.
Cardiology 





Neurology 





Kastelein JJ, van Leuven SI, Burgess L, et al. Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia. N Engl J Med 2007;356:1620–30.
Cardiology 





Endocrine 





Genetics 





Oh BH, Mitchell J, Herron JR, et al. Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension. J Am Coll Cardiol 2007;49:1157–63.
Cardiology 





Nephrology 





Greenspan SL, Nelson JB, Trump DL, et al. Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: a randomized trial. Ann Intern Med 2007;146:416–24.
Endocrine 





Oncology 





Surgery/urology 





Sazawal S, Dhingra U, Dhingra P, et al. Effects of fortified milk on morbidity in young children in north India: community based, randomised, double masked placebo controlled trial. BMJ 2007;334:140.
Infectious disease 





Tropical & travel medicine 





Paediatrics 





Public health 





Chaillet N, Dumont A. Evidence-based strategies for reducing cesarean section rates: a meta-analysis. Birth 2007;34:53–64.[CrossRef][Medline]
Obstetrics 





Armon C, Argoff CE, Samuels J, et al. Assessment: use of epidural steroid injections to treat radicular lumbosacral pain: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2007;68:723–9.
Neurology 





Physical medicine & rehabilitation 





Surgery/orthopaedics 





Siddiqi N, Stockdale R, Britton A, et al. Interventions for preventing delirium in hospitalised patients. Cochrane Database Syst Rev 2007;(2):CD005563.[Medline]
Surgery/Orthopaedics 





Clasen T, Schmidt WP, Rabie T, et al. Interventions to improve water quality for preventing diarrhoea: systematic review and meta-analysis. BMJ 2007;334:782.
Tropical & travel medicine 





Public health 





Bebb C, Kendrick D, Coupland C, et al. A cluster randomised controlled trial of the effect of a treatment algorithm for hypertension in patients with type 2 diabetes. Br J Gen Pract 2007;57:136–43.[Medline]
GP/FP/Primary care 





Cardiology 





Endocrine 





Bosch-Capblanch X, Abba K, Prictor M, et al. Contracts between patients and healthcare practitioners for improving patients adherence to treatment, prevention and health promotion activities. Cochrane Database Syst Rev 2007;(2):CD004808.[Medline]
GP/FP/Primary care 





Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain 2007;129:210–23.[CrossRef][Medline]
GP/FP/Primary care 





Rheumatology 





Hodge W, Horsley T, Albiani D, et al. The consequences of waiting for cataract surgery: a systematic review. CMAJ 2007;176:1285–90.
GP/FP/Primary care 





Geriatrics 





Page SJ, Levine P, Leonard A. Mental practice in chronic stroke: results of a randomized, placebo-controlled trial. Stroke 2007;38:1293–7.
GP/FP/Primary care 





Neurology 





Physical medicine & rehabilitation 





Roberts L, Ahmed I, Hall S. Intercessory prayer for the alleviation of ill health. Cochrane Database Syst Rev 2007;(1):CD000368.[Medline]
GP/FP/Primary care 





Lanas A, Baron JA, Sandler RS, et al. Peptic ulcer and bleeding events associated with rofecoxib in a 3-year colorectal adenoma chemoprevention trial. Gastroenterology 2007;132:490–7.[CrossRef][Medline]
Gastroenterology 





Liu JL, Wyatt JC, Deeks JJ, et al. Systematic reviews of clinical decision tools for acute abdominal pain. Health Technol Assess 2006;10:1–186.[Medline]
Surgery 





Morino M, Pellegrino L, Castagna E, et al. Acute nonspecific abdominal pain: a randomized, controlled trial comparing early laparoscopy versus clinical observation. Ann Surg 2006;244:881–6.[CrossRef][Medline]
Emergency medicine 





Surgery 





DIAGNOSIS
Jang T, Uzbielo A, Sineff S, et al. Point-of-care urine trypsinogen testing for the diagnosis of pancreatitis. Acad Emerg Med 2007;14:29–34.[CrossRef][Medline]
Emergency medicine 





Surgery 





Batal I, Ericsoussi MB, Cluette-Brown JE, et al. Potential utility of plasma fatty acid analysis in the diagnosis of cystic fibrosis. Clin Chem 2007;53:78–84.
Respirology 





Paediatrics 





Finley JP, Warren AE, Sharratt GP, et al. Assessing childre
s heart sounds at a distance with digital recordings. Pediatrics 2006;118:2322–5.
Cardiology 





Paediatrics 





Kwan G, Isakson SR, Beede J, et al. Short-term serial sampling of natriuretic peptides in patients presenting with chest pain. J Am Coll Cardiol 2007;49:1186–92.
Emergency medicine 





PROGNOSIS
Miyasaka Y, Barnes ME, Bailey KR, et al. Mortality trends in patients diagnosed with first atrial fibrillation: a 21-year community-based study. J Am Coll Cardiol 2007;49:986–92.
GP/FP/Primary care 





Cardiology 





Sayao AL, Devonshire V, Tremlett H. Longitudinal follow-up of "benign" multiple sclerosis at 20 years. Neurology 2007;68:496–500.
Neurology 





AETIOLOGY
Brouwer GM, van Tol AW, Bergink AP, et al. Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheum 2007;56:1204–11.[CrossRef][Medline]
Physical medicine & rehabilitation 





Rheumatology 





Surgery/orthopaedics 





Bukowski R, Smith GC, Malone FD, et al. Fetal growth in early pregnancy and risk of delivering low birth weight infant: prospective cohort study. BMJ 2007;334:836.
GP/FP/Obstetrics 





Obstetrics 





Emberson JR, Ng LL, Armitage J, et al. N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study. J Am Coll Cardiol 2007;49:311–9.
Cardiology 





Neurology 





Hunter DJ, Niu J, Felson DT, et al. Knee alignment does not predict incident osteoarthritis: the Framingham osteoarthritis study. Arthritis Rheum 2007;56:1212–8.[CrossRef][Medline]
Physical medicine & rehabilitation 





Rheumatology 





Surgery/orthopaedics 





QUALITY IMPROVEMENT
Krist AH, Woolf SH, Johnson RE, et al. Patient education on prostate cancer screening and involvement in decision making. Ann Fam Med 2007;5:112–9.
GP/FP/Primary care 





Surgery/urology 





CLINICAL PREDICTION GUIDE
Tong PC, Kong AP, So WY, et al. The usefulness of the International Diabetes Federation and the National Cholesterol Education Programs Adult Treatment Panel III definitions of the metabolic syndrome in predicting coronary heart disease in subjects with type 2 diabetes. Diabetes Care 2007;30:1206–11.
GP/FP/Primary care 





Cardiology 





Endocrine 





Nigrovic LE, Kuppermann N, Macias CG, et al. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA 2007;297:52–60.
Infectious disease 





Emergency medicine





Paediatrics 





Sun BC, Mangione CM, Merchant G, et al. External validation of the San Francisco Syncope Rule. Ann Emerg Med 2007;49:420–7.[CrossRef][Medline]
GP/FP/Primary care 





Emergency medicine 





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