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THERAPEUTICS
Adi Y, Juarez-Garcia A, Wang D, et al. Oral naltrexone as a treatment for relapse prevention in formerly opioid-dependent drug users: a systematic review and economic evaluation. Health Technol Assess 2007;11:1–85.[Medline]
GP/FP/Mental health 





Psychiatry 





Ashton HA, Gao L, Kim LG, et al. Fifteen-year follow-up of a randomized clinical trial of ultrasonographic screening for abdominal aortic aneurysms. Br J Surg 2007;94:696–701.[CrossRef][Medline]
GP/FP/Primary care 





Askie LM, Duley L, Henderson-Smart DJ, et al. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. Lancet 2007;369:1791–8.[CrossRef][Medline]
GP/FP/Primary care 





GP/FP/Obstetrics 





Obstetrics 





Campbell CL, Smyth S, Montalescot G, et al. Aspirin dose for the prevention of cardiovascular disease: a systematic review. JAMA 2007;297:2018–24.
GP/FP/Primary care 





Internal medicine 





Caruso MK, Pekarovic S, Raum WJ, et al. Topical fat reduction from the waist. Diabetes Obes Metab 2007;9:300–3.[CrossRef][Medline]
GP/FP/Primary care 





Charles T, Quinn D, Weatherall M, et al. An audiovisual reminder function improves adherence with inhaled corticosteroid therapy in asthma. J Allergy Clin Immunol 2007;119:811–6.[CrossRef][Medline]
GP/FP/Primary care 





Allergy & immunology 





Respirology 





Paediatrics 





de Bortoli N, Leonardi G, Ciancia E, et al. Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics. Am J Gastroenterol 2007;102:951–6.[CrossRef][Medline]
GP/FP/Primary care 





Gastroenterology 





Dellinger EP, Tellado JM, Soto NE, et al. Early antibiotic treatment for severe acute necrotizing pancreatitis: a randomized, double-blind, placebo-controlled study. Ann Surg 2007;245:674–83.[CrossRef][Medline]
Gastroenterology 





Infectious disease 





Critical care 





Surgery 





Surgery/Gastrointestinal 





Gregg JA, Callaghan GM, Hayes SC, et al. Improving diabetes self-management through acceptance, mindfulness, and values: a randomized controlled trial. J Consult Clin Psychol 2007;75:336–43.[CrossRef][Medline]
GP/FP/Primary care 





Endocrine 





Hackam DG, Spence JD. Combining multiple approaches for the secondary prevention of vascular events after stroke: a quantitative modeling study. Stroke 2007;38:1881–5.
GP/FP/Primary care 





Neurology 





Holbrook A, Labiris R, Goldsmith CH, et al. Influence of decision aids on patient preferences for anticoagulant therapy: a randomized trial. CMAJ 2007;176:1583–7.
GP/FP/Primary care 





Cardiology 





Haematology 





Hueb W, Lopes NH, Gersh BJ, et al. Five-year follow-up of the Medicine, Angioplasty, or Surgery Study (MASS II): a randomized controlled clinical trial of 3 therapeutic strategies for multivessel coronary artery disease. Circulation 2007;115:1082–9.
Internal medicine 





Cardiology 





Surgery/Cardiac 





Hunter KF, Glazener CM, Moore KN. Conservative management for postprostatectomy urinary incontinence. Cochrane Database Syst Rev 2007;(2):CD001843.[Medline]
Surgery/Urology 





Jennings DL, Kalus JS, Coleman CI, et al. Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta-analysis. Diabet Med 2007;24:486–93.[CrossRef][Medline]
Endocrine 





Kang JH, Cook N, Manson J, et al. Low dose aspirin and cognitive function in the womens health study cognitive cohort. BMJ 2007;334:987.
GP/FP/Mental health 





Psychiatry 





Kuna P, Peters MJ, Manjra AI, et al. Effect of budesonide/formoterol maintenance and reliever therapy on asthma exacerbations. Int J Clin Pract 2007;61:725–36.[CrossRef][Medline]
GP/FP/Primary care 





Allergy & immunology 





Respirology 





Lappe JM, Travers-Gustafson D, Davies KM, et al. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007;85:1586–91.
GP/FP/Primary care 





Oncology 





Ludman EJ, Simon GE, Tutty S, et al. A randomized trial of telephone psychotherapy and pharmacotherapy for depression: continuation and durability of effects. J Consult Clin Psychol 2007;75:257–66.[CrossRef][Medline]
GP/FP/Primary care 





GP/FP/Mental Health 





Psychiatry 





Manguso F, Balzano A. Meta-analysis: the efficacy of rectal beclomethasone dipropionate vs. 5-aminosalicylic acid in mild to moderate distal ulcerative colitis. Aliment Pharmacol Ther 2007;26:21–9.[Medline]
GP/FP/Primary care 





Marini H, Minutoli L, Polito F, et al. Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial. Ann Intern Med 2007;146:839–47.
GP/FP/Primary care 





Gynaecology 





McCallum Z, Wake M, Gerner B, et al. Outcome data from the LEAP (Live, Eat and Play) trial: a randomized controlled trial of a primary care intervention for childhood overweight/mild obesity. Int J Obes (Lond) 2007;31:630–6.[Medline]
Paediatrics 





Mirza SK, Deyo RA. Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain. Spine 2007;32:816–23.[CrossRef][Medline]
GP/FP/Primary care 





Physical medicine & rehabilitation 





Morkved S, Salvesen KA, Schei B, et al. Does group training during pregnancy prevent lumbopelvic pain? A randomized clinical trial. Acta Obstet Gynecol Scand 2007;86:276–82.[CrossRef][Medline]
GP/FP/Obstetrics 





Physical medicine & rehabilitation 





Obstetrics 





Mussano F, Ciccone G, Ceccarelli M, et al. Bone morphogenetic proteins and bone defects: a systematic review. Spine 2007;32:824–30.[CrossRef][Medline]
Surgery/Orthopaedics 





Peters SP, Anthonisen N, Castro M, et al. Randomized comparison of strategies for reducing treatment in mild persistent asthma. N Engl J Med 2007;356:2027–39.
GP/FP/Primary care 





Allergy & immunology 





Respirology 





Paediatrics 





Rao SS, Mudipalli RS, Remes-Troche JM, et al. Theophylline improves esophageal chest pain--a randomized, placebo-controlled study. Am J Gastroenterol 2007;102:930–8.[CrossRef][Medline]
Gastroenterology 





Taubert D, Roesen R, Lehmann C, et al. Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial. JAMA 2007;298:49–60.
Cardiology 





Tseng MY, Hutchinson PJ, Czosnyka M, et al. Effects of acute pravastatin treatment on intensity of rescue therapy, length of inpatient stay, and 6-month outcome in patients after aneurysmal subarachnoid hemorrhage. Stroke 2007;38:1545–50.
Neurology 





Vilsboll T, Zdravkovic M, Le-Thi T, et al. Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes. Diabetes Care 2007;30:1608–10.
Endocrine 





Wang X, Qin X, Demirtas H, et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet 2007;369:1876–82.[CrossRef][Medline]
GP/FP/Primary care 





Neurology 





Weymiller AJ, Montori VM, Jones LA, et al. Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial. Arch Intern Med 2007;167:1076–82.
GP/FP/Primary care 





Endocrine 





Wilson J, Yao GL, Raftery J, et al. A systematic review and economic evaluation of epoetin alfa, epoetin beta and darbepoetin alfa in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technol Assess 2007;11:1–220.[Medline]
GP/FP/Primary care 





Haematology 





Oncology 





Surgery/Oncology 





Zalmanovici A, Yaphe J. Steroids for acute sinusitis. Cochrane Database Syst Rev 2007;(2):CD005149.[Medline]
GP/FP/Primary care 





Infectious disease 





Emergency medicine 





AETIOLOGY
Blais L, Beauchesne MF, Rey E, et al. Use of inhaled corticosteroids during the first trimester of pregnancy and the risk of congenital malformations among women with asthma. Thorax 2007;62:320–8.
GP/FP/Primary care 





GP/FP/Obstetrics 





Respirology 





Obstetrics 





Cao JJ, Arnold AM, Manolio TA, et al. Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation 2007;116:32–8.
Cardiology 





Neurology 





Huerta C, Johansson S, Wallander MA, et al. Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom. Arch Intern Med 2007;167:935–43.
GP/FP/Primary care 





Emergency medicine 





QUALITY IMPROVEMENT
Clancy DE, Huang P, Okonofua E, et al. Group visits: promoting adherence to diabetes guidelines. J Gen Intern Med 2007;22:620–4.[CrossRef][Medline]
Endocrine 





ECONOMICS
Tappenden P, Chilcott J, Eggington S, et al. Option appraisal of population-based colorectal cancer screening programmes in England. Gut 2007;56:677–84.
Gastroenterology 





CLINICAL PREDICTION GUIDE
Gibson SC, Payne CJ, Byrne DS, et al. B-type natriuretic peptide predicts cardiac morbidity and mortality after major surgery. Br J Surg 2007;94:903–9.[CrossRef][Medline]
Cardiology 





Surgery 





Surgery/Cardiac 





Surgery/Gastrointestinal 





Surgery/Vascular 





Weiner DE, Tighiouart H, Griffith JL, et al. Kidney disease, Framingham risk scores, and cardiac and mortality outcomes. Am J Med 2007;120:552.
GP/FP/Primary care 





Nephrology 





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