Prophylactic use of antiplatelet agents (largely low dose aspirin) v control (placebo or no antiplatelet agent) in women at risk of developing pre-eclampsia*
| Outcomes | Number of trials (n) | Weighted event rates | RRR (95% CI) | NNT (CI) | |
|---|---|---|---|---|---|
| Antiplatelet agents | Control | ||||
| *Abbreviations defined in glossary; weighted event rates calculated from data in article using a fixed effects model. | |||||
| Pre-eclampsia | 43 (33 439) | 6.3% | 7.7% | 19% (12 to 25) | 69 (51 to 109) |
| Preterm birth (<37 wks) | 28 (31 845) | 16.1% | 17.3% | 7% (2 to 11) | 83 (50 to 238) |
| Fetal and neonatal deaths | 38 (34 010) | 2.4% | 2.8% | 16% (4 to 26) | 250 (125 to ∞) |
| Small for gestational age | 32 (24 310) | 7.6% | 8.6% | 8% (0 to 15) | 100 (100 to ∞) |
