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Therapeutics
Review: oestrogen improves symptoms of overactive bladder in postmenopausal women

https://doi.org/10.1136/ebm.10.2.50

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    Cardozo L, Lose G, McClish D, Versi E. A systematic review of the effects of estrogens for symptoms suggestive of overactive bladder. Acta Obstet Gynecol Scand 2004;83:892–7.
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 Q In postmenopausal women with symptoms suggestive of overactive bladder (OAB) (urge or stress incontinence), does oestrogen therapy reduce symptoms more than placebo?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Gynaecology ★★★★★☆☆

    METHODS

    Embedded ImageData sources:

    studies were identified by searching Medline, EMBASE/Excerpta Medica, Science Citation Index (January 1969 to December 1999), and reference lists of articles; and hand searching urology, gynaecology, gerontology, and primary care medicine journals.

    Embedded ImageStudy selection and assessment:

    studies in any language were selected if they were randomised controlled trials (RCTs) that were published or presented at a scientific meeting, reported symptoms suggestive of OAB (including frequency, urgency, or urge incontinence), and compared oestrogen with placebo.

    Embedded ImageOutcomes:

    diurnal frequency, nocturnal frequency, incontinence episodes, urgency, first sensation to void, and bladder capacity. …

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