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Computed tomographic colonography without cathartic preparation performed well in detecting colorectal polyps

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 Q What is the diagnostic performance of low dose multidetector computed tomographic colonography (CTC) without bowel cathartic preparation compared with optical colonoscopy for detection of colonic polyps?

Clinical impact ratings IM/Ambulatory care ★★★★★★☆ Oncology ★★★★★☆☆ Gastroenterology ★★★★★☆☆ Geriatrics ★★★★★☆☆

METHODS

Embedded ImageDesign:

blinded comparison of CTC with optical colonoscopy.

Embedded ImageSetting:

a university hospital in Rome, Italy.

Embedded ImagePatients:

203 patients ⩾35 years of age (mean age 61 y, 69% men) who were scheduled to have optical colonoscopy because of average risk colorectal cancer screening, personal or family history of colorectal polyps, family history of colorectal cancer, abnormal screening test result, iron deficiency anaemia, haematochezia, change in bowel habits, abdominal pain, or weight loss. Exclusion criteria were history of familial adenomatous polyposis or hereditary non-polyposis cancer syndromes; previous colorectal surgery; suspected inflammatory bowel disease, bowel obstruction, or acute diverticulitis; contraindications …

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