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Evid Based Med 10:73 doi:10.1136/ebm.10.3.73
  • Therapeutics

Review: statins reduce stroke but not stroke mortality

Statins v placebo or usual care for stroke reduction*

Weighted event rates
Outcomes at 0.3–6.1 years Number of trials (n) Intervention Control RRR (95% CI) NNT (CI)
*Abbreviations defined in glossary; weighted event rates, RRR, NNT, and CI calculated from data in article using a fixed effects model.
All stroke 26 (94 128) 2.9% 3.4% 20% (14 to 25) 222 (163 to 350)
Fatal stroke 15 (71 967) 0.68% 0.69% 8% (−10 to 23) Not significant
Haemorrhagic stroke 7 (43 758) 0.29% 0.34% 9% (−26 to 34) Not significant

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