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Diagnosis
Multislice computed tomography detected coronary artery disease

https://doi.org/10.1136/ebm.11.1.24

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    Hoffmann MH, Shi H, Schmitz BL, et al. Noninvasive coronary angiography with multislice computed tomography. JAMA 2005;293:2471–8.
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 Q What is the diagnostic accuracy of multislice computed tomography (MSCT) in patients with suspected coronary artery disease (CAD)?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Cardiology ★★★★★★☆

    METHODS

    Embedded ImageDesign:

    blinded comparison of MSCT with conventional invasive coronary angiography.

    Embedded ImageSetting:

    a university hospital in Ulm, Germany.

    Embedded ImagePatients:

    103 patients (mean age 62 y, 69% men) with suspected CAD. Exclusion criteria included contraindication to iodinated contrast, renal dysfunction, hyperthyroidism, previous surgical revascularisation, and acute coronary syndrome.

    Embedded ImageDescription of test:

    all patients received MSCT examinations using a scanner with 16 detector rows (Brilliance 16, Philips Medical Systems, Cleveland, OH, USA). Contrast flow rate was adapted according to a test bolus acquisition. Pitch settings were modified according to …

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    Footnotes

    • For correspondence: Dr M H Hoffmann, University Hospital, Ulm, Germany. martin.hoffmann{at}uniklinik-ulm.de

    • Source of funding: State Government of Baden-Wuerttemberg, Germany.