Article Text

PDF
Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications in hypertension

Statistics from Altmetric.com


 
 Q In patients 40–79 years of age with hypertension and ⩾3 other cardiovascular (CV) risk factors, is amlodipine plus perindopril more effective than atenolol plus bendroflumethiazide for reducing CV outcomes?

Clinical Impact Ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★★☆ Cardiology ★★★★★★☆

METHODS

Embedded ImageDesign

randomised controlled trial (Anglo-Scandinavian Cardiac Outcomes Trial–Blood Pressure Lowering Arm [ASCOT-BPLA]).

Embedded ImageAllocation

concealed.*

Embedded ImageBlinding

blinded (outcome assessors).*

Embedded ImageFollow up period

median 5.5 years.

Embedded ImageSetting

686 family practices in the Nordic countries and 32 regional centres in the UK and Ireland.

Embedded ImagePatients

19 257 patients 40–79 years of age (mean age 63 y, 77% men) who had hypertension and ⩾3 other CV risk factors. Exclusion criteria included previous myocardial infarction (MI), currently treated angina, and a cerebrovascular event …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Glossary
    BMJ Publishing Group Ltd