Article Text

PDF
Glucosamine and chondroitin sulphate did not improve pain in osteoarthritis of the knee

Statistics from Altmetric.com


 
 Q In patients with osteoarthritis of the knee, are glucosamine, chondroitin sulphate, or both more effective than placebo for relief of pain?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★☆☆ Rheumatology ★★★★★★☆ Physical medicine & rehabilitation ★★★★★★★

METHODS

Embedded ImageDesign

randomised placebo controlled trial. (Glucosamine/chondroitin Arthritis Intervention Trial [GAIT]).

Embedded ImageAllocation

unclear allocation concealment.*

Embedded ImageBlinding

blinded (clinicians and patients).*

Embedded ImageFollow-up period

6 months.

Embedded ImageSetting

16 clinical centres in the US.

Embedded ImagePatients

1583 patients ⩾40 years of age (mean age 59 y, 54% women) who had knee pain for ⩾6 months and on most days of the previous month; radiographic evidence of osteoarthritis; score 125–400 on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); and American Rheumatism Association functional class …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.