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Q In patients with pulmonary embolism (PE), can those who are at low risk of short term mortality (and candidates for outpatient treatment) be identified from medical history and clinical findings?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Internal medicine ★★★★★★☆ Emergency medicine ★★★★★★☆
METHODS
Design:
separate derivation, internal validation, and external validation cohorts.
Setting:
186 non-governmental hospitals in Pennsylvania, USA (derivation and internal validation cohorts) and 3 university hospitals in Switzerland and France (external validation cohort).
Patients:
15 531 inpatients ⩾18 years of age (45% ⩾70 y of age, 60% women) with a primary discharge diagnosis of acute PE were randomly divided into derivation (n = 10 354) and internal validation (n = 5177) cohorts. The external validation cohort consisted of 221 patients (49% ⩾70 y of age, 55% women) with confirmed PE who had presented …
Footnotes
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For correspondence: Dr D Aujesky, University of Lausanne, Lausanne, Switzerland. aujesky{at}swissonline.ch
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Source of funding: US National Heart, Lung, and Blood Institute.